Dr Francesca Filbey
The University of Texas at Dallas, Dallas, TX, USA
Chair, Dr Francesca Filbey, introduces the expert panel and agenda for this discussion on cannabinoids and cognition in multiple sclerosis.
Regulated cannabis products are FDA-approved or seeking FDA approval. Unregulated cannabis products are not FDA-approved nor seeking FDA approval. There are currently no FDA-approved cannabis products for MS in the USA.view bio and disclosures 1/4 Next Chapter
Differentiating the effects of cannabis vs cannabinoids on adult cognition
Dr Francesca Filbey provides an overview of the current understanding of the different effects of acute and chronic use of cannabis and specific cannabinoids on cognition, the differences between regulated and unregulated cannabis products, and the limitations of published data.
Regulated cannabis products are FDA-approved or seeking FDA approval. Unregulated cannabis products are not FDA-approved nor seeking FDA approval. There are currently no FDA-approved cannabis products for MS in the USA.view bio and disclosures 2/4 Next Chapter
Cognitive decline in MS
Dr Ralph Benedict outlines the prevalence of cognitive decline in multiple sclerosis, the specific domains typically impaired, impact of decline on daily living, and recovery from decline.
Regulated cannabis products are FDA-approved or seeking FDA approval. Unregulated cannabis products are not FDA-approved nor seeking FDA approval. There are currently no FDA-approved cannabis products for MS in the USA.view bio and disclosures 3/4 Next Chapter
Cannabis and cognition in persons with MS
Dr Sarah Morrow discusses the details of studies that have assessed the effect of cannabis on cognition in persons with multiple sclerosis, both as a primary and secondary endpoint, in addition to the impact of discontinuing unregulated cannabis in these individuals.
Overview & Learning Objectives
Cannabis contains more than 500 components, of which over 100 cannabinoids have presently been identified.1 Cannabis and the specific cannabinoids Δ-9 tetrahydrocannabinol and cannabidiol have been investigated for their effects on cognition.2–23
Watch three leading experts discuss the effects of cannabis and cannabinoids on the cognitive processes of adults, how multiple sclerosis affects cognition and the impact of cannabis on cognition in multiple sclerosis.
After watching this activity, you should be able to:
- Differentiate the effects of cannabis vs. specific cannabinoids on adult cognitive processes
- Discuss how multiple sclerosis affects cognition
- Summarise the data regarding the impact of cannabis on cognition in persons with multiple sclerosis
Faculty & Disclosures
Dr Francesca Filbey
The University of Texas at Dallas, Dallas, TX, USA
Dr Francesca Filbey, PhD, is a Professor of Cognitive Neuroscience and Director of Cognitive Neuroscience Research of Addictive Disorders at the Center for BrainHealth, School of Behavioral and Brain Sciences at The University of Texas at Dallas, and an Adjunct Associate Professor at the University of Texas Southwestern Medical School, Department of Psychiatry.
Disclosures: Dr Filbey discloses: research funded by the National Institute of Drug Abuse and through the Bert Moore Endowed Chair; Consultancy Fees from Greenwich Biosciences, Inc.
Dr Ralph Benedict
University at Buffalo, State University of New York, Buffalo, NY, USA
Dr Ralph Benedict, PhD, is a professor of neurology and psychiatry at the University at Buffalo, State University of New York (SUNY) where he directs clinical neuropsychology and provides services for the Jacobs Multiple Sclerosis Center and the UB Alzheimer’s Disease and Memory Disorders Center.
Disclosures: Dr Benedict discloses: received honoraria, speaking, or consulting fees from Greenwich Biosciences, Inc, Biogen, Celgene, EMD Serono, Genentech, Medday, Novartis, and Roche; research support from Biogen, Genentech, and Novartis; and royalties from Psychological Assessment Resources.
Dr Sarah Morrow
Western University, London, ON, Canada
Dr Sarah Morrow, MD, is an Associate Professor in the Department of Clinical Neurological Sciences at Western University (London, ON) and Director of the London (ON) MS Clinic.
Disclosures: Dr Morrow discloses: received consulting fees from Greenwich Biosciences, Inc; served on advisory boards for Biogen Idec, EMD Serono, Genzyme Canada, Novartis, and Roche; has received Investigator Initiated Grant Funds from Biogen Idec, Novartis, and Roche; has acted as site PI for multi-center trials funded by Novartis, Genzyme, Roche, and AbbVie.
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